20.06.2008, 12:24
Gehört auch noch dazu....:
Zitat:Interessenkonflikt
Prof. Dr. med. Marcus Maurer ist als Berater für Biofrontera AG, essex pharma GmbH, Schering-Plough und Uriach Pharma tätig und hat Honorare für Vorträge von Almirall Hermal GmbH, Biofrontera AG, essex pharma GmbH, Novartis Pharma GmbH und Schering-Plough erhalten. Marcus Maurer führt Studien und grundlagenwissenschaftliche Forschungsprojekte durch, die von Almirall Hermal GmbH, Biofrontera AG essex pharma GmbH, Novartis Pharma GmbH, Schering-Plough, UCB und Uriach Pharma unterstützt werden.
Prof. Dr. med. Jürgen Grabbe ist als Berater für Novartis Pharma GmbH tätig und hat Honorare für Vorträge von essex pharma GmbH erhalten. Er führt Studien durch, die von Novartis Pharma GmbH und Schering-Plough finanziert werden.
Manuskriptdaten
eingereicht: 16. 1. 2008, revidierte Fassung angenommen: 30. 4. 2008
Anschrift für die Verfasser
Prof. Dr. med. Marcus Maurer
Klinik für Dermatologie, Venerologie und Allergologie
Charité - Universitätsmedizin Berlin
Charitéplatz 1, 10117 Berlin
E-Mail: marcus.maurer@charite.de
Summary
Urticaria: Its History-Based Diagnosis and Etiologically
Oriented Treatment
Introduction: The term \"urticaria\" refers to any of a group of distinct skin conditions that are characterized by itchy, wheal-and-flare skin reactions (hives). In spontaneous urticaria, the most common type, the hives seem to arise without provocation. Methods: Selective review of the literature, including current guidelines. Results: Spontaneous urticaria is divided into acute (lasting less than six weeks) and chronic types. The pathognomonic itching, hives, and angioedema arise by the same mechanism - cutaneous mast cell activation and release of histamin and other mediators of inflammation - in both acute and chronic urticaria, but these two disorders have different etiological profiles. The underlying cause of acute urticaria cannot be identified in about half of all cases. Chronic urticaria, which is much rarer, is usually caused by autoreactivity, chronic infection, or intolerance to food additives. If the condition persists after the underlying cause has been treated or eliminated, non-sedating antihistamines are the agents of first choice for symptomatic treatment. Discussion: Unlike acute urticaria, which is self-limited and should be treated symptomatically, chronic urticaria should be treated by the identification and elimination of underlying causes, which is usually curative.
Dtsch Arztebl 2008; 105(25): 458-66
The English version of this article is available online:
www.aerzteblatt-international.de