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Sesam - Allergie
#1
Sesame allergy: a growing food allergy of global proportions?
Authors: Gangur, Venu; Kelly, Caleb1; Navuluri, Lalitha1
Source: Annals of Allergy, Asthma and Immunology, Volume 95, Number 1, July 2005, pp. 4-11(8)
Publisher:American College of Allergy, Asthma, & Immunology


http://www.ingentaconnect.com/content/ac....henrietta

Abstract:
Objective: To present an up-to-date synopsis on the global prevalence, natural history, nature of allergens, and immune mechanisms of sesame allergy.
Data Sources: We performed a literature search using the PubMed database. We obtained information on regulatory issues from the Web pages of respective agencies.
Study Selection: The PubMed search was performed using the algorithm sesame AND allergy. Date restriction was not used, and only articles in English were considered. The articles obtained were screened for additional references to work not obtained in the initial search. Each article was analyzed, and a pooled source of published information was generated.
Results: Evidence was found for increased reporting of sesame allergy during the past 5 decades, with reports mostly from developed countries. Clinically, most sesame allergy was presented in at least 2 major forms: (1) immediate hypersensitivity, often expressed as systemic anaphylaxis, associated with positive skin prick test and/or IgE antibody test results to sesame proteins with some cross-reactivity with other foods, and (2) delayed hypersensitivity to lignin-like compounds in sesame oil clinically expressed as contact allergic dermatitis. There were a few cases of immediate hypersensitivity to sesame with negative skin prick test and/or IgE antibody test results that were confirmed by oral challenge tests.
Conclusions: Sesame allergy is a significant, serious, and growing problem. Evidence exists of the ability of protein and oil components of sesame to trigger immediate hypersensitivity via IgE antibody and delayed hypersensitivity via cell-mediated immune responses, respectively.
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Sesam-Allergie: Eine zunehmende Nahrungsmittelallergie mit globaler Bedeutung?
Eine Meta – Analyse der bisherigen Publikationen zu Sesamallergie....
Fazit: Sesamallergie ist ein bedeutendes, ernstes und zunehmendes Problem. Es gibt Hinweise darauf, dass Sesamproteine und Sesamölbestandteile die Fähigkeit haben, eine sofortige , IgE-vermittelte Hypersensitivität sowie eine verzögerte, durch zelluläre Immunreaktionen bedingte Hypersensitivität auszulösen.

( gehört - leider- mit zu den Ölsaaten, die in der Regel einem Allergiker "Kummer" bereiten können....)

Uli
Antworten
#2
V53. Sesam als Auslöser schwerer anaphylaktischer
Reaktionen
Sabine Dölle, E. Fiedler, T. Zuberbier, M. Worm
Klinik für Dermatologie, Venerologie und Allergologie; Charité -
Universitätsmedizin Berlin, Berlin.
http://www.dermatologie-mainz.de/uploads...gr2007.pdf


In einer Vorschau auf das Tagungsprogramm vom 16./ 17. März im Allergo Journal 2007;16
wird der Fall einer Sesam-Allergie vorgestellt :.
Wichtigstes Fazit hierbei :gerösteter Sesam vervielfacht - so wie Erdnüsse – sein allergenes Potenzial um ein Vielfaches . Reaktionen auf z.B. Sesambrötchen oder in Sesamöl Gebratenes können also darauf zurückzuführen sein.


Uli
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