27.02.2005, 16:58
Lactose intolerance and intestinal villi morphology in Thai people.
Thong-Ngam D, Suwangool P, Prempracha J, Tangkijvanich P, Vivatvekin B, Sriratanabun A.
Department of Physiology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
OBJECTIVE: To study the relationship of lactose intolerance and intestinal villi morphology in Thai people. MATERIAL AND METHOD: Subjects for this study were patients with functional dyspepsia who had no history of milk allergy and underwent gastroduodenoscopy. Two mucosal biopsy specimens were taken from beyond the distal end of the second part of the duodenum. The specimens were carefully orientated and were graded according to the following scheme: group I: finger shaped villi; group II: mixed finger and leaf shaped villi; group III: clubbing or blunting shaped villi. All subjects were tested for lactose malabsorption by breath hydrogen analysis after consuming 50 gram lactose. Breath hydrogen concentration was analyzed in samples collected intermittently by end-expiratory technique. A rise in breath hydrogen concentration of 20 PPM over baseline was considered evidence of lactose malabsorption. RESULTS: The twenty-five subjects were twenty females (80.0%) and five males (20.0%) who ranged in age from 18 to 53 years (mean 31 +/- 8.29). Sixteen subjects belonged to the finger shaped villi group (64.0%), five to the mixed finger and leaf shaped villi, group (20.0%) and four to the clubbing or blunting shaped villi group (16.0%). Results of breath hydrogen excretion test identified the prevalence of lactose intolerance in 68 per cent of the subjects : 15/16 (93.75%) of group I; 1/5 (20.0%) of group II and 1/4 (25%) of group III respectively (P<0.001). The symptom of diarrhea after lactose loading was correlated well in patients who had positive breath hydrogen analysis. CONCLUSION: As shown in this study, the lactose intolerance is not related to intestinal villi morphology. It is implied that primary lactase deficiency is more common in Thai people than secondary lactase deficiency.
PMID: 11758841 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query...s=11758841
o.a. Studie ergab wohl, dass in Thailand die primäre ( also genetische Veranlagung) der LI sehr viel häufiger ist als die sekundäre ( Folge einer Darmerkrankung o.ä.)
und nun dieses – völlig Unverständliche …….
Khon Kaen pilots fluoridated milk
BANGKOK, Feb 19 (TNA) – Several countries have introduced fluoride into their water supplies to help prevent childhood tooth decay, but the Ministry of Public Health is to go one further by putting fluoride into the milk distributed to schoolchildren in Thailand's north-eastern province of Khon Kaen to solve the province’s shocking dental problems. The move comes after research from 2001 showing that 88.7 percent of all 5-6 year-old children in the province suffered from tooth decay, while 59 percent of all 12 year-olds faced the same problem.Today Dr. Somyos Charoensak, Director-General of the Department of Health, said that the Khon Kaen pilot project would follow on from a similar programme in Bangkok, where the Department of Health works with the Chitralada Foundation and the Faculty of Dentistry at Thammasat University to provide fluoridated milk to schools.The programme receives academic support from the World Health Organization (WHO) and financial support from the UK-based Borrow Foundation.Figures which suggest that the Bangkok project has reduced rates of dental decay by as much as 27 percent have prompted the Department of Health to extend the project to provincial areas.Dr. Somyos said that several measures had already been instituted in Khon Kaen in an attempt to bring down the appalling rates of dental decay, including compulsory tooth brushing after lunch for all primary school children.The fluoridation project will be run in conjunction with the national dairy producers, who will introduce fluoride to both pasteurized and UHT milk. (TNA)--E006
http://www.mcot.org/query.php?nid=35964
Man kann daraus eigentlich nur schließen, dass Milch auf nicht nur einem Auge "blind" macht....
Uli
Thong-Ngam D, Suwangool P, Prempracha J, Tangkijvanich P, Vivatvekin B, Sriratanabun A.
Department of Physiology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
OBJECTIVE: To study the relationship of lactose intolerance and intestinal villi morphology in Thai people. MATERIAL AND METHOD: Subjects for this study were patients with functional dyspepsia who had no history of milk allergy and underwent gastroduodenoscopy. Two mucosal biopsy specimens were taken from beyond the distal end of the second part of the duodenum. The specimens were carefully orientated and were graded according to the following scheme: group I: finger shaped villi; group II: mixed finger and leaf shaped villi; group III: clubbing or blunting shaped villi. All subjects were tested for lactose malabsorption by breath hydrogen analysis after consuming 50 gram lactose. Breath hydrogen concentration was analyzed in samples collected intermittently by end-expiratory technique. A rise in breath hydrogen concentration of 20 PPM over baseline was considered evidence of lactose malabsorption. RESULTS: The twenty-five subjects were twenty females (80.0%) and five males (20.0%) who ranged in age from 18 to 53 years (mean 31 +/- 8.29). Sixteen subjects belonged to the finger shaped villi group (64.0%), five to the mixed finger and leaf shaped villi, group (20.0%) and four to the clubbing or blunting shaped villi group (16.0%). Results of breath hydrogen excretion test identified the prevalence of lactose intolerance in 68 per cent of the subjects : 15/16 (93.75%) of group I; 1/5 (20.0%) of group II and 1/4 (25%) of group III respectively (P<0.001). The symptom of diarrhea after lactose loading was correlated well in patients who had positive breath hydrogen analysis. CONCLUSION: As shown in this study, the lactose intolerance is not related to intestinal villi morphology. It is implied that primary lactase deficiency is more common in Thai people than secondary lactase deficiency.
PMID: 11758841 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query...s=11758841
o.a. Studie ergab wohl, dass in Thailand die primäre ( also genetische Veranlagung) der LI sehr viel häufiger ist als die sekundäre ( Folge einer Darmerkrankung o.ä.)
und nun dieses – völlig Unverständliche …….
Khon Kaen pilots fluoridated milk
BANGKOK, Feb 19 (TNA) – Several countries have introduced fluoride into their water supplies to help prevent childhood tooth decay, but the Ministry of Public Health is to go one further by putting fluoride into the milk distributed to schoolchildren in Thailand's north-eastern province of Khon Kaen to solve the province’s shocking dental problems. The move comes after research from 2001 showing that 88.7 percent of all 5-6 year-old children in the province suffered from tooth decay, while 59 percent of all 12 year-olds faced the same problem.Today Dr. Somyos Charoensak, Director-General of the Department of Health, said that the Khon Kaen pilot project would follow on from a similar programme in Bangkok, where the Department of Health works with the Chitralada Foundation and the Faculty of Dentistry at Thammasat University to provide fluoridated milk to schools.The programme receives academic support from the World Health Organization (WHO) and financial support from the UK-based Borrow Foundation.Figures which suggest that the Bangkok project has reduced rates of dental decay by as much as 27 percent have prompted the Department of Health to extend the project to provincial areas.Dr. Somyos said that several measures had already been instituted in Khon Kaen in an attempt to bring down the appalling rates of dental decay, including compulsory tooth brushing after lunch for all primary school children.The fluoridation project will be run in conjunction with the national dairy producers, who will introduce fluoride to both pasteurized and UHT milk. (TNA)--E006
http://www.mcot.org/query.php?nid=35964
Man kann daraus eigentlich nur schließen, dass Milch auf nicht nur einem Auge "blind" macht....
Uli